Current studies have demonstrated that innate immunity possesses memory characteristics.Although the molecular mechanisms underlying innate immune memory have been addressed by numerous studies, genetic variations in innate immune memory and the associated genes remain unclear.Here, we explored innate immune memory in 163 lines of Drosophila melano
Hepcidin, a short peptide synthesized primarily by hepatocytes in response to increased body iron and inflammation, is a crucial iron-regulating factor.Hepcidin regulates intestinal iron absorption and releases iron from macrophages into plasma through a negative iron feedback mechanism.The discovery of hepcidin inspired a torrent of research into
Abstract Background In high throughput cancer genomic studies, results from the analysis of single datasets often suffer from a lack of reproducibility because of small sample sizes.Integrative analysis can effectively pool and analyze multiple datasets and provides a cost effective way to improve reproducibility.In integrative analysis, simultaneo
Central Asia is an area characterized by complex tectonics and active deformation; the related seismic activity controls the earthquake hazard level that, due to the occurrence of secondary and tertiary effects, also has direct implications for the hazard related to mass movements such as landslides, which are responsible for an extensive number of